SCHEMBL11928362

SCHEMBL11928362

Cn1nnnc1C(C)(C)F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
ABCC9 O60706 1/20 0.33
ABCC8 Q09428 1/20 0.33
KCNJ11 Q14654 1/20 0.33
KCNJ8 Q15842 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11928363 0.86 ALDH1A1 (0.40) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL4409218 0.79 ALDH1A1 (0.34) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL11928138 0.79 ALDH1A1 (0.34) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL18572773 0.76 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL14037128 0.76 ALDH1A1 (0.35) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL13663804 0.73 ALDH1A1 (0.38) ALDH1A1
SCHEMBL4414658 0.65 ALDH1A1 (0.37) ALDH1A1
SCHEMBL4399613 0.65 ALDH1A1 (0.30) ALDH1A1
SCHEMBL4407943 0.64
SCHEMBL4409023 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484676-A2 Tetrazol-substituted anthranilic acid amides as pesticides Bayer CropScience AG (DE) 2012-08-08 EP disclosed