SCHEMBL11928366

SCHEMBL11928366

Cn1nnc(C(C)(C)F)n1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34
RECQL P46063 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11928336 0.86 NPC1 (0.31) NPC1TP53RECQLRAB9ASMN1; SMN2
SCHEMBL4409011 0.80 NPC1 (0.36) NPC1TP53RECQLRAB9ASMN1; SMN2
SCHEMBL11928293 0.79
SCHEMBL4405630 0.79
SCHEMBL24050933 0.76 TSHR (0.34)
SCHEMBL11928290 0.76 GAA (0.32)
SCHEMBL19361202 0.74
SCHEMBL4405977 0.73 TSHR (0.31)
SCHEMBL19344898 0.73 TSHR (0.35) RECQL
SCHEMBL19344902 0.70 NPC1 (0.31) NPC1TP53RECQLRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484676-A2 Tetrazol-substituted anthranilic acid amides as pesticides Bayer CropScience AG (DE) 2012-08-08 EP disclosed