Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11928366 | 0.70 | NPC1 (0.34) | NPC1TP53RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL11928336 | 0.70 | NPC1 (0.31) | NPC1TP53RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL4405977 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL19344898 | 0.67 | TSHR (0.35) | RECQLTSHR | |
| SCHEMBL15367994 | 0.66 | — | — | |
| SCHEMBL24050933 | 0.61 | TSHR (0.34) | TSHR | |
| SCHEMBL11928290 | 0.61 | GAA (0.32) | — | |
| SCHEMBL15368033 | 0.60 | FAAH (0.39) | NPC1TP53RECQLRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28773484 | 0.55 | FAAH (0.41) | NPC1TP53RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL4411052 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156493-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2017-09-14 | — | — | WO | disclosed |