⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916542 | 0.86 | — | — | |
| SCHEMBL8911903 | 0.80 | ACACB (0.33) | — | |
| SCHEMBL10122822 | 0.80 | ACACB (0.33) | — | |
| SCHEMBL17641845 | 0.72 | — | — | |
| SCHEMBL4788962 | 0.69 | NPC1 (0.37) | — | |
| SCHEMBL19487728 | 0.69 | — | — | |
| SCHEMBL14864778 | 0.68 | MME (0.32) | — | |
| SCHEMBL19483453 | 0.68 | — | — | |
| SCHEMBL14850463 | 0.68 | MME (0.32) | — | |
| SCHEMBL10141033 | 0.66 | SCN9A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242156-B2 | Linked dibenzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2012-08-14 | — | — | US | disclosed |
| US-20100221215-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2010-09-02 | — | — | US | disclosed |