Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 12/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2543881 | 0.84 | AAK1 (0.33) | CA1CTSKCTSSCA12CA7 | |
| SCHEMBL2543878 | 0.84 | AAK1 (0.33) | CA1CTSKCTSSCA12CA7 | |
| SCHEMBL7228766 | 0.84 | AAK1 (0.33) | CA1CTSKCTSSCA12CA7 | |
| SCHEMBL2326465 | 0.83 | CA2 (0.40) | CA2CA1MAPK1 | |
| SCHEMBL8911416 | 0.83 | CA2 (0.40) | CA2CA1MAPK1 | |
| SCHEMBL17512264 | 0.82 | AAK1 (0.33) | CA12CA14AAK1 | |
| SCHEMBL9702539 | 0.79 | MAPT (0.40) | — | |
| SCHEMBL9773246 | 0.79 | MAPT (0.40) | — | |
| SCHEMBL9773244 | 0.79 | MAPT (0.40) | — | |
| SCHEMBL9773214 | 0.79 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212065-B2 | Method for the production of optically active alpha alkyl carbonyl compounds | ALBERT-LUDWIGS-UNIVERSITAT FREIBURG (DE) | 2012-07-03 | — | — | US | disclosed |