Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.75 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.71 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17929041 | 0.89 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL17074687 | 0.87 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL17074689 | 0.87 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL27667798 | 0.87 | ADRB2 (0.82) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL775235 | 0.87 | ADRB2 (0.82) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL27667945 | 0.86 | ADRB2 (0.76) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL3838704 | 0.86 | ADRB2 (0.85) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL3844087 | 0.86 | ADRB2 (0.85) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL776967 | 0.86 | ADRB2 (0.76) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL5708324 | 0.86 | ADRB2 (0.80) | ADRB2ADRB1ADRB3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242135-B2 | Biphenyl derivatives | THERAVANCE, INC. (US) | 2012-08-14 | — | — | US | disclosed |