Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996420 | 0.91 | HDAC1 (0.34) | HDAC1SUCNR1CA1CA2PTGS1 | |
| SCHEMBL11932631 | 0.87 | CA12 (0.40) | HDAC1CA1CA2IDO1NPC1 | |
| SCHEMBL85496 | 0.86 | PTGS1 (0.37) | HDAC1PTGS1MAPK14NPC1RAB9A | |
| SCHEMBL10198582 | 0.85 | PLK4 (0.37) | HDAC1PTGS1MAPK14NPC1RAB9A | |
| SCHEMBL85722 | 0.85 | PTGS1 (0.44) | HDAC1CA1CA2PTGS1NPC1 | |
| SCHEMBL4798877 | 0.83 | IDO1 (0.41) | CA1CA2IDO1NPC1RAB9A | |
| SCHEMBL14117688 | 0.82 | HDAC1 (0.42) | HDAC1SUCNR1CA1CA2PTGS1 | |
| SCHEMBL10198572 | 0.81 | PTGS1 (0.41) | HDAC1PTGS1MAPK14RAB9ASMN1; SMN2 | |
| SCHEMBL15176889 | 0.81 | KIF11 (0.46) | HDAC1PTGS1RAB9AMEN1MAPT | |
| SCHEMBL16284384 | 0.81 | PTGS1 (0.41) | HDAC1PTGS1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160151314-A1 | Facially Amphiphilic Polymers and Oligomers and Uses Thereof | NATIONAL SCIENCE FOUNDATION | 2016-06-02 | — | — | US | disclosed |
| US-9241917-B2 | Facially amphiphilic polymers and oligomers and uses thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-01-26 | — | — | US | disclosed |
| US-9241917-B2 | Facially amphiphilic polymers and oligomers and uses thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-01-26 | — | — | US | disclosed |
| US-8236800-B2 | antimicrobial agents and antidote for hemorrhagic complications associated with heparin therapy; peptide having optimal sites of polar and nonpolar substituents that confer amphiphilic properties; leucine and aminobenzoic acid derivative; isophthalic acid and diaminobenzene, 3-tert-butyl-6-alkylthio cmpd | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160151314-A1 | Facially Amphiphilic Polymers and Oligomers and Uses Thereof | TLR3, ABHD16A, ANTXR2 | HDAC1 1308/4885SUCNR1 4032/4885CA1 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.