Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 0.77 |
| ▸ | CA2 | P00918 | 19/20 | 0.77 |
| ▸ | CA12 | O43570 | 17/20 | 0.77 |
| ▸ | CA4 | P22748 | 13/20 | 0.77 |
| ▸ | CA9 | Q16790 | 13/20 | 0.77 |
| ▸ | CA6 | P23280 | 2/20 | 0.68 |
| ▸ | CA5A | P35218 | 2/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15094416 | 0.86 | CA1 (0.75) | CA1CA2CA12CA4CA9 | |
| SCHEMBL16682342 | 0.84 | GAA (0.59) | CA1CA2CA12CA4CA9 | |
| SCHEMBL6273619 | 0.83 | CA1 (0.60) | CA1CA2CA12CA4CA9 | |
| Hydrochloric Acid SCHEMBL6270652 | 0.82 | CA1 (0.59) | CA1CA2CA12CA4CA9 | |
| SCHEMBL13030968 | 0.81 | CA1 (1.00) | CA1CA2CA12CA4CA9 | |
| SCHEMBL579379 | 0.80 | CA1 (0.84) | CA1CA2CA12CA4CA9 | |
| SCHEMBL23202943 | 0.78 | CA1 (1.00) | CA1CA2CA12CA4CA9 | |
| SCHEMBL16129968 | 0.78 | CA2 (0.70) | CA1CA2CA12CA4CA9 | |
| SCHEMBL13123502 | 0.78 | CA1 (0.70) | CA1CA2CA12CA4CA9 | |
| SCHEMBL13716534 | 0.78 | CA2 (0.70) | CA1CA2CA12CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150507-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| US-9150507-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| US-8227618-B2 | Amine-derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20100273841-A1 | AMINE-DERIVATIVES HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY AND THE USES THEREOF | SHIONOGI & CO., LTD. (JP) | 2010-10-28 | — | — | US | disclosed |
| US-20100063027-A1 | Amine Derivative Having NPY Y5 Receptor Antagonistic Activity | SHIONOGI & CO., LTD. (JP) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063027-A1 | Amine Derivative Having NPY Y5 Receptor Antagonistic Activity | NPY5R, NPY1R, NPY2R | CA1 2981/4885CA2 1202/4885CA12 3342/4885 |
| US-20100273841-A1 | AMINE-DERIVATIVES HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY AND THE USES THEREOF | NPY5R, NPY1R, NPY2R | CA1 2434/4885CA2 1168/4885CA12 2605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.