Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 19/20 | 0.57 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937175 | 0.88 | CCR9 (0.55) | CCR9CCR2SERPINE1 | |
| SCHEMBL11936682 | 0.88 | CCR9 (0.72) | CCR9CCR2SERPINE1 | |
| SCHEMBL11938267 | 0.87 | CCR9 (0.55) | CCR9CCR2SERPINE1 | |
| SCHEMBL343923 | 0.85 | CCR9 (0.76) | CCR9CCR2 | |
| SCHEMBL10284624 | 0.84 | CCR9 (0.51) | CCR9CCR2SERPINE1 | |
| SCHEMBL12474674 | 0.83 | CCR9 (0.63) | CCR9CCR2 | |
| SCHEMBL2616486 | 0.80 | CCR9 (0.48) | CCR9 | |
| SCHEMBL11937065 | 0.78 | CCR9 (0.52) | CCR9CCR2SERPINE1 | |
| SCHEMBL11936681 | 0.78 | CCR9 (0.53) | CCR9CCR2SERPINE1 | |
| SCHEMBL14034474 | 0.77 | CCR9 (0.53) | CCR9CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211896-B2 | Aryl sulfonamides | CHEMOCENTRYX, INC. (US) | 2012-07-03 | — | — | US | disclosed |
| US-20110021523-A1 | ARYL SULFONAMIDES | CHEMOCENTRYX, INC. (US) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021523-A1 | ARYL SULFONAMIDES | CCR9, CCR1, CCR2 | CCR9 1/4885CCR2 3/4885SERPINE1 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.