Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.77 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.76 |
| ▸ | BCHE | P06276 | 1/20 | 0.72 |
| ▸ | P4HB | P07237 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21002197 | 0.91 | MAOB (0.86) | MAOBABCG2BCHEP4HBCYP1A2 | |
| SCHEMBL31298986 | 0.91 | MAOB (0.86) | MAOBABCG2BCHEP4HBCYP1A2 | |
| SCHEMBL15807286 | 0.88 | ABCG2 (0.62) | MAOBABCG2BCHEP4HBCYP1A2 | |
| SCHEMBL15631514 | 0.87 | ABCG2 (0.89) | MAOBABCG2BCHEP4HBCYP1A2 | |
| SCHEMBL7771481 | 0.87 | MAOB (0.79) | MAOBABCG2BCHEP4HBCYP1A2 | |
| SCHEMBL18551752 | 0.87 | MAOB (0.79) | MAOBBCHEP4HBCYP1A2CYP1A1 | |
| SCHEMBL9341818 | 0.87 | ABCG2 (0.89) | MAOBABCG2BCHEP4HBCYP1A2 | |
| SCHEMBL7771478 | 0.87 | MAOB (0.79) | MAOBABCG2BCHEP4HBCYP1A2 | |
| SCHEMBL8987072 | 0.87 | MAOB (1.00) | MAOBABCG2BCHEP4HBCYP1A2 | |
| SCHEMBL8987069 | 0.87 | MAOB (1.00) | MAOBABCG2BCHEP4HBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140171503-A1 | NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER | HUMAN SERVICES (US) | 2014-06-19 | — | — | US | disclosed |
| US-8227616-B2 | Cyanopyridine antibacterial agents and methods of use thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | FDPS, CYP3A5, ABCG2 | MAOB 387/4885ABCG2 3/4885BCHE 768/4885 |
| US-20140171503-A1 | NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER | AR, NCOA1, NR5A1 | MAOB 3966/4885ABCG2 742/4885BCHE 4460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.