SCHEMBL119379

SCHEMBL119379

O=C(N[C@@H](Cn1cncn1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.66
TP53 P04637 3/20 0.66
MDM2 Q00987 7/20 0.57
CASP3 P42574 2/20 0.46
SLC17A5 Q9NRA2 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1829788 1.00 MDM4 (0.66) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL30353583 1.00 MDM4 (0.66) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL120638 0.84 MDM4 (0.67) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL119548 0.84 MDM4 (0.67) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL19815024 0.82 MDM4 (0.67) MDM4TP53MDM2CASP3
SCHEMBL19815022 0.82 MDM4 (0.67) MDM4TP53MDM2CASP3
SCHEMBL8895610 0.79 MDM4 (0.62) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL14432835 0.79 MDM4 (0.59) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL14788958 0.79 MDM4 (0.59) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL1486216 0.78 MDM4 (0.61) MDM4TP53MDM2CASP3SLC17A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed