Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14788958 | 1.00 | MDM4 (0.59) | MDM4TP53SLC17A5CASP3KMT2A | |
| SCHEMBL18881272 | 0.94 | MDM4 (0.54) | MDM4TP53SLC17A5CASP3KMT2A | |
| SCHEMBL3436129 | 0.91 | MDM4 (0.58) | MDM4TP53SLC17A5CASP3KMT2A | |
| SCHEMBL29400770 | 0.91 | MDM4 (0.58) | MDM4TP53SLC17A5CASP3KMT2A | |
| SCHEMBL1001473 | 0.91 | MDM4 (0.58) | MDM4TP53SLC17A5CASP3KMT2A | |
| SCHEMBL30665728 | 0.90 | MDM4 (0.51) | MDM4TP53SLC17A5CASP3KMT2A | |
| SCHEMBL16310689 | 0.90 | MDM4 (0.57) | MDM4TP53SLC17A5CASP3KMT2A | |
| SCHEMBL10020438 | 0.90 | MDM4 (0.54) | MDM4TP53SLC17A5CASP3MDM2 | |
| SCHEMBL1739174 | 0.90 | MDM4 (0.54) | MDM4TP53SLC17A5CASP3MDM2 | |
| SCHEMBL22154133 | 0.89 | MDM4 (0.56) | MDM4TP53SLC17A5CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765817-B1 | Selective inhibitors of EG5 motors and methods of use | ARROWHEAD CENTER, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-8349899-B1 | Selective inhibitors of EG5 motors and methods of use | ARROWHEAD CENTER, INC. (US) | 2013-01-08 | — | — | US | disclosed |