⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107730 | 0.84 | — | — | |
| SCHEMBL24201502 | 0.82 | — | — | |
| SCHEMBL4811100 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL30135528 | 0.72 | — | — | |
| SCHEMBL3469508 | 0.67 | — | — | |
| SCHEMBL5334495 | 0.67 | — | — | |
| SCHEMBL6979374 | 0.67 | — | — | |
| SCHEMBL4790319 | 0.67 | — | — | |
| SCHEMBL5803917 | 0.65 | SLC6A1 (0.65) | — | |
| SCHEMBL10942196 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032480-A1 | Treatment of ischemia-induced arrhythmias | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-02-08 | — | — | US | claimed |
| WO-2006138487-A2 | TREATMENT OF ISCHEMIA-INDUCED ARRHYTHMIAS | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-12-28 | — | — | WO | claimed |
| EP-1250597-A2 | IDENTIFICATION OF PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | MITOKOR (US) | 2002-10-23 | — | — | EP | claimed |
| WO-2001051922-A2 | IDENTIFICATION OF PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | MITOKOR (US) | 2001-07-19 | — | — | WO | claimed |
| EP-2247558-B2 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | LILLY CO ELI (US) | 2024-07-03 | — | — | EP | disclosed |
| EP-2663338-B1 | GLUCOSE-BASED OLIGOSACCHARIDES COMPRISING A POSITRON-EMITTING RADIONUCLIDE AND THEIR USE FOR IMAGING | UNIV EMORY (US) | 2024-03-06 | — | — | EP | disclosed |
| EP-4324483-A2 | OLIGOSACCHARIDE CONJUGATES FOR TARGETING BACTERIA AND USES RELATED THERETO | Emory University (US) | 2024-02-21 | — | — | EP | disclosed |
| US-11844846-B2 | Styrylbenzothiazole derivatives and uses in imaging methods | EMORY UNIVERSITY (US) | 2023-12-19 | — | — | US | disclosed |
| US-20230158178-A1 | Radionuclide Tracers of 1-Amino-3,4-Difluorocyclopentane-1-Carboxylic Acid, Derivatives, and Uses Thereof | UNIV EMORY (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4121121-A1 | RADIONUCLIDE TRACERS OF 1-AMINO-3,4-DIFLUOROCYCLOPENTANE-1-CARBOXYLIC ACID, DERIVATIVES, AND USES THEREOF | Emory University (US) | 2023-01-25 | — | — | EP | disclosed |
| US-20220306663-A1 | Metal Tricarbonyl Complexes Comprising Substituted Iminodiactic Acid Ligands and Uses as Radioisotope Tracers | UNIV EMORY (US) | 2022-09-29 | — | — | US | disclosed |
| US-11384106-B2 | Metal tricarbonyl complexes comprising substituted iminodiactic acid ligands and uses as radioisotope tracers | EMORY UNIVERSITY (US) | 2022-07-12 | — | — | US | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| US-5776946-A | Peripheral benzodiazepine receptor ligands as antiinflammatory agents | MCGEER, EDITH G. (CA) | 1998-07-07 | — | — | US | disclosed |
| EP-0546164-A1 | INDOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | FIDIA RESEARCH FOUNDATION (US) | 1993-06-16 | — | — | EP | disclosed |
| US-5206382-A | INDOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | FIDIA GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1993-04-27 | — | — | US | disclosed |
| WO-1993000334-A1 | INDOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | FIDIA - GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1993-01-07 | — | — | WO | disclosed |
| EP-0455805-A1 | A METHOD OF STIMULATING STEROIDOGENESIS WITH ALPIDEM | FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1991-11-13 | — | — | EP | disclosed |
| US-5032595-A | Method of stimulating steroidogenesis with alpidem | FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1991-07-16 | — | — | US | disclosed |
| WO-1991007961-A1 | A METHOD OF STIMULATING STEROIDOGENESIS WITH ALPIDEM | FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1991-06-13 | — | — | WO | disclosed |