Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.31 |
| ▸ | TSPO | P30536 | 2/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11939240 | 1.00 | MAPT (0.35) | MAPTSMN1; SMN2SERPINE1CAMKK1CAMKK2 | |
| SCHEMBL12223556 | 0.97 | MAPT (0.33) | MAPTSMN1; SMN2SERPINE1CAMKK1CAMKK2 | |
| SCHEMBL15381579 | 0.95 | MAPT (0.37) | MAPTSMN1; SMN2CAMKK1CAMKK2FPR2 | |
| SCHEMBL15381720 | 0.95 | MAPT (0.37) | MAPTSMN1; SMN2CAMKK1CAMKK2FPR2 | |
| SCHEMBL14922594 | 0.92 | MAPT (0.36) | MAPTSMN1; SMN2CAMKK1CAMKK2FPR2 | |
| SCHEMBL12836812 | 0.91 | FPR2 (0.38) | MAPTSMN1; SMN2CAMKK1CAMKK2FPR2 | |
| SCHEMBL12836057 | 0.91 | FPR2 (0.38) | MAPTSMN1; SMN2CAMKK1CAMKK2FPR2 | |
| SCHEMBL11939070 | 0.90 | SERPINE1 (0.38) | MAPTSERPINE1TYRKMT2A | |
| SCHEMBL11939341 | 0.90 | SERPINE1 (0.38) | MAPTSERPINE1TYRKMT2A | |
| SCHEMBL14922550 | 0.90 | MAPT (0.40) | MAPTSMN1; SMN2CAMKK1CAMKK2MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580147-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| US-20120168677-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120168677-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CXCR1, OCIAD1, LEO1 | MAPT 1566/4885SMN1; SMN2 4683/4885SERPINE1 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.