Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAG | P20916 | 5/20 | 0.48 |
| ▸ | SELE | P16581 | 5/20 | 0.43 |
| ▸ | SIGLEC7 | Q9Y286 | 5/20 | 0.40 |
| ▸ | CD22 | P20273 | 3/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940310 | 0.93 | SELE (0.48) | MAGSELESIGLEC7CD22SELL | |
| SCHEMBL15958438 | 0.86 | SELE (0.49) | MAGSELESIGLEC7CD22SELL | |
| SCHEMBL11940309 | 0.86 | SELE (0.57) | MAGSELESIGLEC7SELLSELP | |
| SCHEMBL18159145 | 0.77 | SELL (0.51) | MAGSELESIGLEC7SELLSELP | |
| SCHEMBL16273961 | 0.77 | MAG (0.64) | MAGSELESIGLEC7SELLSELP | |
| SCHEMBL16272797 | 0.77 | MAG (0.64) | MAGSELESIGLEC7SELLSELP | |
| SCHEMBL18159157 | 0.76 | SIGLEC7 (0.39) | MAGSELESIGLEC7SELLSELP | |
| SCHEMBL18165662 | 0.75 | SELL (0.52) | MAGSELESIGLEC7SELLSELP | |
| SCHEMBL11940303 | 0.75 | MAG (0.62) | MAGSELESIGLEC7CD22SELL | |
| SCHEMBL15958441 | 0.75 | CD22 (0.49) | MAGSIGLEC7CD22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9259476-B2 | Monophosphorylated lipid A derivatives | WAYNE STATE UNIVERSITY (US) | 2016-02-16 | — | — | US | disclosed |
| US-20140356367-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | WAYNE STATE UNIVERSITY | 2014-12-04 | — | — | US | disclosed |
| US-8809285-B2 | Monophosphorylated lipid A derivatives | WAYNE STATE UNIVERSITY (US) | 2014-08-19 | — | — | US | disclosed |
| US-20120190633-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140356367-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | SGMS1, PCYT1A, PHOSPHO1 | MAG 758/4885SELE 2374/4885SIGLEC7 490/4885 |
| US-20120190633-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | SGMS1, PCYT1A, PHOSPHO1 | MAG 758/4885SELE 2374/4885SIGLEC7 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.