Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.44 |
| ▸ | ACACA | Q13085 | 6/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940681 | 0.90 | PGR (0.44) | ACACBACACAPTGS1PTGS2PGR | |
| SCHEMBL11940692 | 0.87 | ACACB (0.33) | ACACBACACAPTGS1PTGS2PGR | |
| SCHEMBL11940689 | 0.87 | ACACB (0.34) | ACACBACACAPTGS1PTGS2PGR | |
| SCHEMBL11940676 | 0.86 | ACACB (0.41) | ACACBACACAPGRHSD17B1ESR1 | |
| SCHEMBL11940690 | 0.86 | ACACB (0.33) | ACACBACACAPTGS1PTGS2HSD17B1 | |
| SCHEMBL11940691 | 0.86 | ACACB (0.33) | ACACBACACAPGRHSD17B1ESR1 | |
| SCHEMBL11940693 | 0.86 | ACACB (0.33) | ACACBACACAPGRHSD17B1ESR1 | |
| SCHEMBL11940684 | 0.86 | COMT (0.37) | ACACBACACAPGR | |
| SCHEMBL10195147 | 0.86 | HTR2A (0.36) | ACACBACACAPTGS1PTGS2 | |
| SCHEMBL11940682 | 0.85 | CHEK1 (0.39) | ACACBACACAPGRHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741806-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-06-03 | — | — | US | disclosed |
| US-8741806-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-06-03 | — | — | US | disclosed |
| US-20120190545-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190545-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-26 | — | — | US | disclosed |
| WO-2011006543-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190545-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | ACACB 1002/4885ACACA 1274/4885PTGS1 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.