Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914089 | 0.88 | CES2 (0.67) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL61183 | 0.88 | — | — | |
| SCHEMBL1505348 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL17493405 | 0.86 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL16143265 | 0.86 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL9094627 | 0.86 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| Ammonia Solution, Strong SCHEMBL902138 | 0.86 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL9064565 | 0.86 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| Hydrochloric Acid SCHEMBL1704886 | 0.86 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| Hydrochloric Acid SCHEMBL30998088 | 0.86 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029660-B | P2X3And/or P2X2/3Compounds and methods | 阿萨纳生物科技有限责任公司 | 2019-11-15 | — | — | CN | claimed |
| CN-110461854-A | Process for preparing chiral 2, 3-dihydrothiazolo [3,2-A ] pyrimidin-4-ium compounds | BASF SE | 2019-11-15 | — | — | CN | claimed |
| CN-110267953-A | Tetrahydroimidazo [4,5-C ] pyridine derivatives as inducers of PD-L1 internalization | 因赛特公司 | 2019-09-20 | — | — | CN | claimed |
| CN-105814040-B | The condensed 1,4- dihydro two of inhibitor as thermal excited transcryption factor 1 dislikes ene derivative | 癌症研究科技有限公司 | 2019-07-30 | — | — | CN | claimed |
| CN-109952302-A | Muscarine M1 receptor forward direction allosteric modulators | 苏文生命科学有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-109890819-A | Heterocyclic compound as immunomodulator | 因赛特公司 | 2019-06-14 | — | — | CN | claimed |
| CN-104926801-B | Substituted azetidine analog derivative, the pharmaceutical composition containing it and its application in antitumor | 浙江大学 | 2019-06-04 | — | — | CN | claimed |
| CN-106164047-B | 1,2- substituted cyclopentane as orexin receptor antagonists | 武田药品工业株式会社 | 2019-04-16 | — | — | CN | claimed |
| CN-105209449-B | Inhibitors of the kynurenine pathway | 库拉德夫制药私人有限公司 | 2019-02-01 | — | — | CN | claimed |
| CN-106170486-B | Novel indazolecarboxamides, method for the production thereof, pharmaceutical preparations containing the same and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2019-01-15 | — | — | CN | claimed |
| CN-107484415-A | 1-cyanopyrrolidine compounds as USP30 inhibitors | 特殊治疗有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-107231802-A | Heterocyclic derivatives and use thereof | 株式会社C&C新药研究所 | 2017-10-03 | — | — | CN | claimed |
| CN-103384668-B | compounds and compositions for inhibition of NAMPT | 福马TM有限责任公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106458984-A | 5, 6-disubstituted pyridine-2-carboxamides as cannabinoid receptor agonists | 豪夫迈·罗氏有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106456619-A | Bicyclic heterocyclic derivatives as IRAK4 inhibitors | 奥列基因发现技术有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106456582-A | TrkA kinase inhibitors, compositions and methods thereof | 默沙东公司 | 2017-02-22 | — | — | CN | claimed |
| CN-104072480-B | Quinolines and its preparation method and application | 沈阳药科大学 | 2016-12-28 | — | — | CN | claimed |
| CN-103958473-B | Amide compound, composition and application thereof | ADVINUS THERAPEUTICS LTD. (IN) | 2016-11-30 | — | — | CN | claimed |
| CN-106029660-A | P2X 3 and/or P2X 2/3 compounds and methods | 阿萨纳生物科技有限责任公司 | 2016-10-12 | — | — | CN | claimed |
| CN-103874686-B | Piperidine derivatives and compositions for inhibition of nicotinamide phosphoribosyltransferase (NAMPT) | 福马TM有限责任公司 | 2016-08-17 | — | — | CN | claimed |