Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 14/20 | 0.42 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194091 | 1.00 | C3AR1 (0.42) | C3AR1PTGESKMT2ALTA4HPTGS2 | |
| SCHEMBL3693796 | 1.00 | C3AR1 (0.42) | C3AR1PTGESKMT2ALTA4HPTGS2 | |
| SCHEMBL1177782 | 0.93 | C3AR1 (0.40) | C3AR1KMT2A | |
| SCHEMBL1177785 | 0.93 | C3AR1 (0.40) | C3AR1KMT2A | |
| SCHEMBL1178118 | 0.93 | C3AR1 (0.40) | C3AR1KMT2A | |
| SCHEMBL1193476 | 0.92 | C3AR1 (0.40) | C3AR1PTGESKMT2A | |
| Bicarbonate SCHEMBL3693977 | 0.90 | C3AR1 (0.45) | C3AR1KMT2A | |
| SCHEMBL1194163 | 0.89 | C3AR1 (0.42) | C3AR1 | |
| SCHEMBL12872154 | 0.89 | C3AR1 (0.42) | C3AR1 | |
| SCHEMBL1194161 | 0.89 | C3AR1 (0.42) | C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987256-B2 | Oxo-heterocyclic substituted carboxylic acid derivatives and the use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| US-20110034450-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIEGESELLSCHAFT (DE) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034450-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF | OTC, PC, HCAR2 | C3AR1 1349/4885PTGES 224/4885KMT2A 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.