SCHEMBL11941208

SCHEMBL11941208

c1ccc2cc(-c3c4ccccc4c(-c4ccc5ccccc5c4)c4cc(-c5ccc(-c6nccc7c6sc6ccccc67)cn5)ccc34)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.38
HTR5A P47898 1/20 0.38
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
NPC1 O15118 2/20 0.31
CYP1A2 P05177 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
CCNT1 O60563 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CDK9 P50750 1/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30606988 0.90 HTR2B (0.45) HTR2BHTR5ACYP11B1CYP11B2NPC1
SCHEMBL11030653 0.90 HTR2B (0.45) HTR2BHTR5ACYP11B1CYP11B2NPC1
SCHEMBL11941212 0.89 HTR2B (0.44) HTR2BHTR5ACYP11B1CYP11B2NPC1
SCHEMBL11941207 0.88 HTR2B (0.44) HTR2BHTR5ACYP11B1CYP11B2MAPT
SCHEMBL11941218 0.86 HTR2B (0.44) HTR2BHTR5ACYP11B1CYP11B2NPC1
SCHEMBL11941217 0.85 HTR2B (0.45) HTR2BHTR5ACYP11B1CYP11B2NPC1
SCHEMBL20909409 0.84 HTR2B (0.41) HTR2BHTR5AMAPTALOX5MAPK9
SCHEMBL11941211 0.84 HTR2B (0.40) HTR2BHTR5AMAPTKDM4EALOX5
SCHEMBL11941215 0.84 HTR2B (0.40) HTR2BHTR5AALDH1A1MAPTALOX5
SCHEMBL13759461 0.82 HTR2B (0.41) HTR2BHTR5ACYP11B1CYP11B2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8415031-B2 Electron transporting compounds UNIVERSAL DISPLAY CORPORATION (US) 2013-04-09 US disclosed
US-8415031-B2 Electron transporting compounds UNIVERSAL DISPLAY CORPORATION (US) 2013-04-09 US disclosed
US-20120187381-A1 Electron Transporting Compounds UNIVERSAL DISPLAY CORPORATION (US) 2012-07-26 US disclosed
US-20120187381-A1 Electron Transporting Compounds UNIVERSAL DISPLAY CORPORATION (US) 2012-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120187381-A1 Electron Transporting Compounds SLC19A2, ABCB7, SLCO2B1 HTR2B 2238/4885HTR5A 3346/4885CYP11B1 381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.