SCHEMBL20909409

SCHEMBL20909409

c1ccc2c(c1)-c1ccccc1-c1ccc(-c3c4ccccc4c(-c4ccc5ccccc5c4)c4cc(-c5nccc6c5sc5ccccc56)ccc34)cc1-c1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.41
HTR5A P47898 1/20 0.41
ALOX5 P09917 1/20 0.36
MAPK9 P45984 2/20 0.33
MAPK10 P53779 2/20 0.33
S1PR4 O95977 3/20 0.31
S1PR5 Q9H228 3/20 0.31
MAPKAPK2 P49137 1/20 0.31
PRKDC P78527 1/20 0.31
MAPK8 P45983 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11030653 0.94 HTR2B (0.45) HTR2BHTR5AALOX5MAPK9MAPK10
SCHEMBL30606988 0.94 HTR2B (0.45) HTR2BHTR5AALOX5MAPK9MAPK10
SCHEMBL11941212 0.92 HTR2B (0.44) HTR2BHTR5AALOX5MAPK9MAPK10
SCHEMBL11941215 0.91 HTR2B (0.40) HTR2BHTR5AALOX5MAPK9MAPK10
SCHEMBL20909407 0.90 ALOX5 (0.38) ALOX5PRKDCMAPT
SCHEMBL11941211 0.89 HTR2B (0.40) HTR2BHTR5AALOX5MAPK9MAPK10
SCHEMBL11941207 0.89 HTR2B (0.44) HTR2BHTR5AALOX5MAPK9MAPK10
SCHEMBL21702871 0.88 ALOX5 (0.43) HTR2BHTR5AALOX5MAPK9MAPK10
SCHEMBL11941218 0.87 HTR2B (0.44) HTR2BHTR5AALOX5MAPK9MAPK10
SCHEMBL26179822 0.86 HTR2B (0.39) HTR2BHTR5AALOX5MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201290-B2 Tetraphenylene anthracene compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-12-14 US disclosed
US-20190115541-A1 TETRAPHENYLENE ANTHRACENE COMPOUNDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190115541-A1 TETRAPHENYLENE ANTHRACENE COMPOUNDS TRPA1, SLC29A2, XPOT HTR2B 3863/4885HTR5A 3956/4885ALOX5 2952/4885
US-11201290-B2 Tetraphenylene anthracene compounds TRPA1, SLC29A2, XPOT HTR2B 3863/4885HTR5A 3956/4885ALOX5 2952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.