SCHEMBL11941273

CN(C)c1ccc(N(c2ccc(N(C)C)cc2)c2ccc(N(c3ccc(/C=C(\C#N)C(=O)O)cc3)c3ccc(N(c4ccc(N(C)C)cc4)c4ccc(N(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.91

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	2/20	0.66

▸	MAPT	P10636	2/20	0.66

▸	KMT2A	Q03164	2/20	0.66

▸	ALDH1A1	P00352	2/20	0.66

▸	CISD1	Q9NZ45	1/20	0.59

▸	KDM4E	B2RXH2	1/20	0.59

▸	SLC16A3	O15427	1/20	0.59

▸	CYP3A4	P08684	1/20	0.59

▸	HPGD	P15428	1/20	0.59

▸	SLC16A1	P53985	1/20	0.59

▸	GPR35	Q9HC97	1/20	0.59

▸	EGFR	P00533	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15129044	1.00	MEN1 (0.66)	MEN1MAPTKMT2AALDH1A1CISD1
SCHEMBL15129043	1.00	MEN1 (0.66)	MEN1MAPTKMT2AALDH1A1CISD1
SCHEMBL5950754	0.95	MEN1 (0.71)	MEN1MAPTKMT2AALDH1A1CISD1
SCHEMBL16544440	0.95	MEN1 (0.71)	MEN1MAPTKMT2AALDH1A1CISD1
SCHEMBL5950751	0.95	MEN1 (0.71)	MEN1MAPTKMT2AALDH1A1CISD1
SCHEMBL12672953	0.92	CISD1 (0.69)	ALDH1A1CISD1KDM4ESLC16A3CYP3A4
SCHEMBL12639966	0.92	CISD1 (0.69)	ALDH1A1CISD1KDM4ESLC16A3CYP3A4
SCHEMBL29502532	0.92	CISD1 (0.69)	ALDH1A1CISD1KDM4ESLC16A3CYP3A4
SCHEMBL12661978	0.88	CISD1 (0.59)	ALDH1A1CISD1KDM4ESLC16A3CYP3A4
SCHEMBL10046554	0.88	CISD1 (0.59)	ALDH1A1CISD1KDM4ESLC16A3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8227690-B2	Dye-sensitized photoelectric conversion device	NIPPON KAYAKU KABUSHIKI KAISHA (JP)	2012-07-24	—	—	US	disclosed