SCHEMBL11941575

CN(C)c1ccc(N(c2ccc(C(=C/C=C/C=C(\C#N)C(=O)O)c3ccc(N(c4ccc(N(C)C)cc4)c4ccc(N(C)C)cc4)cc3)cc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	APP	P05067	2/20	0.48

▸	MAPT	P10636	5/20	0.46

▸	ALDH1A1	P00352	4/20	0.46

▸	MEN1	O00255	3/20	0.46

▸	KMT2A	Q03164	3/20	0.46

▸	SLC16A3	O15427	1/20	0.41

▸	SLC16A1	P53985	1/20	0.41

▸	HPGD	P15428	2/20	0.39

▸	RAB9A	P51151	3/20	0.39

▸	NPC1	O15118	1/20	0.39

▸	PSMD14	O00487	1/20	0.39

▸	MAPK1	P28482	1/20	0.38

▸	L3MBTL1	Q9Y468	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18319077	0.96	APP (0.51)	APPMAPTALDH1A1MEN1KMT2A
SCHEMBL12299604	0.96	APP (0.51)	APPMAPTALDH1A1MEN1KMT2A
SCHEMBL11957682	0.96	APP (0.51)	APPMAPTALDH1A1MEN1KMT2A
SCHEMBL11941574	0.92	MAPT (0.48)	APPMAPTALDH1A1MEN1KMT2A
SCHEMBL13863858	0.84	MEN1 (0.50)	MAPTALDH1A1MEN1KMT2AMAPK1
SCHEMBL11940666	0.83	APP (0.70)	APPMAPTALDH1A1MEN1KMT2A
SCHEMBL9361101	0.78	APP (0.74)	APPMAPTALDH1A1MEN1KMT2A
SCHEMBL9361107	0.78	APP (0.74)	APPMAPTALDH1A1MEN1KMT2A
SCHEMBL12299609	0.78	APP (0.66)	APPMAPTALDH1A1MEN1KMT2A
SCHEMBL9361331	0.78	APP (0.66)	APPMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8227690-B2	Dye-sensitized photoelectric conversion device	NIPPON KAYAKU KABUSHIKI KAISHA (JP)	2012-07-24	—	—	US	disclosed