SCHEMBL11941574

CN(C)c1ccc(N(c2ccc(C(=C/C=C(\C#N)C(=O)O)c3ccc(N(c4ccc(N(C)C)cc4)c4ccc(N(C)C)cc4)cc3)cc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	6/20	0.48

▸	ALDH1A1	P00352	5/20	0.48

▸	MEN1	O00255	4/20	0.48

▸	KMT2A	Q03164	4/20	0.48

▸	SLC16A3	O15427	1/20	0.43

▸	SLC16A1	P53985	1/20	0.43

▸	APP	P05067	1/20	0.41

▸	HPGD	P15428	2/20	0.41

▸	RAB9A	P51151	3/20	0.41

▸	NPC1	O15118	1/20	0.41

▸	PSMD14	O00487	1/20	0.40

▸	MAPK1	P28482	1/20	0.40

▸	L3MBTL1	Q9Y468	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11941575	0.92	APP (0.48)	MAPTALDH1A1MEN1KMT2ASLC16A3
SCHEMBL11957682	0.87	APP (0.51)	MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL18319077	0.87	APP (0.51)	MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL12299604	0.87	APP (0.51)	MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL11941275	0.85	MAPT (0.49)	MAPTALDH1A1MEN1KMT2ASLC16A3
SCHEMBL15129043	0.78	MEN1 (0.66)	MAPTALDH1A1MEN1KMT2ASLC16A3
SCHEMBL15129044	0.78	MEN1 (0.66)	MAPTALDH1A1MEN1KMT2ASLC16A3
SCHEMBL11941273	0.78	MEN1 (0.66)	MAPTALDH1A1MEN1KMT2ASLC16A3
SCHEMBL11940666	0.77	APP (0.70)	MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL2807525	0.77	KMT2A (0.44)	MAPTALDH1A1MEN1KMT2ASLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8227690-B2	Dye-sensitized photoelectric conversion device	NIPPON KAYAKU KABUSHIKI KAISHA (JP)	2012-07-24	—	—	US	disclosed