⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allylthiourea SCHEMBL4796890 | 0.97 | — | — | |
| Allylthiourea SCHEMBL11884540 | 0.97 | — | — | |
| SCHEMBL1506053 | 0.77 | ALDH1A1 (0.48) | — | |
| SCHEMBL6589055 | 0.74 | — | — | |
| SCHEMBL36968 | 0.74 | — | — | |
| SCHEMBL23327106 | 0.74 | — | — | |
| SCHEMBL5580158 | 0.74 | — | — | |
| SCHEMBL729436 | 0.72 | — | — | |
| SCHEMBL290484 | 0.72 | — | — | |
| SCHEMBL37468 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436429-B1 | BISCARBODIIMIDES AND POLYCARBODIIMIDES AND METHOD FOR THEIR PREPARATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-06-16 | — | — | EP | claimed |
| US-20190023652-A1 | BISCARBODIIMIDES AND POLYCARBODIIMIDES AND METHOD FOR THEIR PREPARATION | DOW GLOBAL TECHNOLOGIES LLC | 2019-01-24 | — | — | US | claimed |
| US-20150158876-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-06-11 | — | — | US | claimed |
| US-8981089-B2 | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-03-17 | — | — | US | claimed |
| US-20130338148-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2013-12-19 | — | — | US | claimed |
| EP-1636236-B1 | PYRAZOLO-QUINAZOLINE DERIVATIVES,PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2013-10-09 | — | — | EP | claimed |
| US-20090124605-A1 | Pyrazolo-Quinazoline Derivatives, Process for Their Preparation and Their Use as Kinase Inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-05-14 | — | — | US | claimed |
| US-20070185143-A1 | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-08-09 | — | — | US | claimed |
| JP-2007502851-A | — | — | 2007-02-15 | — | — | JP | claimed |
| EP-1636236-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES,PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2006-03-22 | — | — | EP | claimed |
| WO-2004104007-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES,PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2004-12-02 | — | — | WO | claimed |
| EP-0940145-B1 | O/W microemulsions containing one or more salts of alkylthiouronium and/or alpha-omega-alkylendithiouronium as microbiocidal agents and their use for manual or automated disinfection of instruments | BODE CHEMIE GMBH & CO (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-0940080-B1 | Disinfecting agent and antiseptic based on alcohols | BODE CHEMIE GMBH & CO (DE) | 2003-01-15 | — | — | EP | claimed |
| EP-0940081-B1 | Combinations of active agents and disinfectants, preservatives and antiseptics containing same | BODE CHEMIE GMBH & CO (DE) | 2002-06-26 | — | — | EP | claimed |
| EP-0355612-B1 | Furylthiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-07-27 | — | — | EP | claimed |
| EP-0355612-A2 | Furylthiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | claimed |
| US-3977880-A | Direct-positive emulsion containing silver halide grains internally doped with metal ions, surface ripened with gold and sulfur compound and fogged by light exposure | FUJI PHOTO FILM CO., LTD. (JA) | 1976-08-31 | — | — | US | claimed |
| JP-54141771-A | — | — | None | — | — | JP | disclosed |
| US-3977880-A | Direct-positive emulsion containing silver halide grains internally doped with metal ions, surface ripened with gold and sulfur compound and fogged by light exposure | FUJI PHOTO FILM CO., LTD. (JA) | 1976-08-31 | — | — | US | disclosed |
| US-3943163-A | FUNGICIDE, MITE OVICIDE | E. I. DU PONT DE NEMOURS & CO. (US) | 1976-03-09 | — | — | US | disclosed |