SCHEMBL11943526

SCHEMBL11943526

COC(C)Oc1ccc(C(C)C(C)(C)C)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPSR1 Q6W5P4 3/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 3/20 0.33
POLB P06746 1/20 0.33
AOC3 Q16853 1/20 0.33
PARP10 Q53GL7 1/20 0.32
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
MEN1 O00255 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TAS1R2 Q8TE23 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24291924 0.82 MEN1 (0.33) MAPK1ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL22882724 0.82 LMNA (0.37) MAPK1NPSR1GAAKMT2AMEN1
SCHEMBL10139336 0.81 MAPK1 (0.52) MAPK1ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL10139335 0.81 MAPK1 (0.52) MAPK1ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL12766982 0.81 MAPK1 (0.52) MAPK1ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL15082378 0.79 MEN1 (0.43) ALDH1A1L3MBTL1KMT2AMEN1
SCHEMBL14584566 0.78 AOC3 (0.33) MAPK1ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL18412091 0.75 ACACB (0.44) MAPK1ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL6273128 0.75 HPGD (0.39) ALDH1A1TSHRTDP1GAAKMT2A
SCHEMBL14227022 0.75 MAPT (0.45) MAPK1ALDH1A1TSHRTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479611-A2 Chemically amplified positive resist composition and patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2012-07-25 EP disclosed