Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13304479 | 0.89 | SMN1; SMN2 (0.55) | MAPTRAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL11943541 | 0.88 | MAPT (0.43) | MAPTRAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL11943588 | 0.85 | ALDH1A1 (0.49) | MAPTSMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL11943590 | 0.83 | ALDH1A1 (0.47) | MAPTRAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL11943609 | 0.83 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL11943581 | 0.83 | ALDH1A1 (0.46) | MAPTRAB9ASMN1; SMN2POLBLMNA | |
| SCHEMBL11943192 | 0.83 | MAPT (0.54) | MAPTRAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL11943584 | 0.82 | ALDH1A1 (0.46) | MAPTRAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL11943583 | 0.82 | ALDH1A1 (0.47) | MAPTRAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL11943612 | 0.82 | MAPT (0.41) | MAPTRAB9ASMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232274-B2 | Pyridazinone derivatives useful as glucan synthase inhibitors | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-07-31 | — | — | US | disclosed |