SCHEMBL119455

SCHEMBL119455

O=C(N[C@@H](Cc1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.59
TP53 P04637 3/20 0.59
CASP3 P42574 2/20 0.54
KMT2A Q03164 2/20 0.51
MDM2 Q00987 4/20 0.51
TNF P01375 1/20 0.51
SLC17A5 Q9NRA2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118169 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL18359346 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29398498 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29367434 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29440768 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL1228254 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29349650 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL30291593 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
Ammonia Solution, Strong SCHEMBL27827995 0.99 MDM4 (0.58) MDM4TP53CASP3KMT2AMDM2
Fluoride SCHEMBL7153172 0.99 MDM4 (0.58) MDM4TP53CASP3KMT2AMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115561372-B Method for detecting related substances in N-fluorenylmethoxycarbonyl-L-phenylalanine 重庆莱美隆宇药业有限公司 2025-04-15 CN claimed
CN-119684406-A Enzyme response self-assembled polypeptide prodrug loaded with camptothecine, preparation and application thereof 东南大学 2025-03-25 CN claimed
CN-117567554-B Gel factor and hydrogel loaded with anti-inflammatory agent as well as preparation methods and application thereof 中国科学技术大学 2025-03-07 CN claimed
CN-119192295-A Neurostatin cyclic peptide and preparation method and application thereof 西北师范大学 2024-12-27 CN claimed
CN-118750438-A Carbamazepine supermolecule hydrogel and preparation method, characterization method and application thereof 山东大学 2024-10-11 CN claimed
CN-116920010-B Preparation method of Yupingfeng compound traditional Chinese medicine preparation 江西新世纪民星动物保健品有限公司 2024-05-31 CN claimed
CN-115521362-B Preparation method of Pseudodestruxin B 哈尔滨工业大学(深圳) 2024-05-28 CN claimed
CN-117924414-A Compound for promoting Abeta clearance and preparation method and application thereof 中山大学 2024-04-26 CN claimed
CN-117659117-A Preparation method of short peptide hydrogel and infrared spectrum analysis method for in-situ characterization of short peptide assembly dynamics process 山东大学 2024-03-08 CN claimed
EP-3423569-B1 3D PRINTING OF A CELLULARISED SCAFFOLD UNIV OXFORD INNOVATION LTD (GB) 2024-02-21 EP claimed
EP-1700244-A4 A METHOD FOR DESIGNING SURFACES BIO LAYER PTY LTD (AU) 2009-07-08 EP claimed
EP-1685134-B1 NOVEL CHELIDONINE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR PRODUCING PHARMACEUTICAL AGENTS SALAMA ZOSER B NAT RER DR (DE) 2009-02-11 EP claimed
CN-101177259-A Method for preparing primary amine carbon nano tube UNIV TONGJI (CN) 2008-05-14 CN claimed
US-20080039483-A1 Novel Chelidonine Derivatives, Methods for the Production Thereof, and Use Thereof For Producing Pharmaceutical Agents SALAMA ZOSER B 2008-02-14 US claimed
US-20070099235-A1 Method for designing surfaces BIO-LAYER PTY LIMITED (AU) 2007-05-03 US claimed
EP-1700244-A1 A METHOD FOR DESIGNING SURFACES Bio-Layer Pty Limited (AU) 2006-09-13 EP claimed
EP-1685134-A1 NOVEL CHELIDONINE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR PRODUCING PHARMACEUTICAL AGENTS Salama, Zoser B. nat.rer.Dr. (DE) 2006-08-02 EP claimed
WO-2005057462-A1 A METHOD FOR DESIGNING SURFACES BIO-LAYER PTY LIMITED (AU) 2005-06-23 WO claimed
WO-2005044820-A1 NOVEL CHELIDONINE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR PRODUCING PHARMACEUTICAL AGENTS SALAMA ZOSER B (DE) 2005-05-19 WO claimed
CN-1490330-A Production of acetooxdralpeptide 上海子能高科股份有限公司 2004-04-21 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080039483-A1 Novel Chelidonine Derivatives, Methods for the Production Thereof, and Use Thereof For Producing Pharmaceutical Agents KIT, MKI67, MCL1 MDM4 3248/4885TP53 49/4885CASP3 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.