SCHEMBL118169

SCHEMBL118169

O=C(N[C@H](Cc1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.59
TP53 P04637 3/20 0.59
CASP3 P42574 2/20 0.54
KMT2A Q03164 2/20 0.51
MDM2 Q00987 4/20 0.51
TNF P01375 1/20 0.51
SLC17A5 Q9NRA2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18359346 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29398498 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29367434 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL119455 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29440768 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL1228254 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29349650 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
SCHEMBL30291593 1.00 MDM4 (0.59) MDM4TP53CASP3KMT2AMDM2
Ammonia Solution, Strong SCHEMBL27827995 0.99 MDM4 (0.58) MDM4TP53CASP3KMT2AMDM2
Fluoride SCHEMBL7153172 0.99 MDM4 (0.58) MDM4TP53CASP3KMT2AMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332299-A1 COMPOUND TARGETING SSTR2, PREPARATION METHOD THEREFOR AND USE THEREOF YANTAI LANNACHENG BIOTECHNOLOGY CO LTD (CN) 2025-10-30 US claimed
EP-4613758-A1 COMPOUNDS TARGETING SSTR2, PREPARATION METHOD THEREFOR, AND USE THEREOF Yantai Lannacheng Biotechnology Co., Ltd. (CN) 2025-09-10 EP claimed
WO-2024120415-A1 COMPOUNDS TARGETING SSTR2, PREPARATION METHOD THEREFOR, AND USE THEREOF 烟台蓝纳成生物技术有限公司 2024-06-13 WO claimed
CN-110357947-B Combretastatin A4 derivative 南京恒远科技开发有限公司 2023-05-26 CN claimed
CN-115583989-B SSTR 2-targeted compound and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2023-02-28 CN claimed
CN-115583989-A SSTR 2-targeted compound and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2023-01-10 CN claimed
CN-113045774-B Double-network composite hydrogel or hydrogel ball containing nano-silver and preparation method and application thereof 江汉大学 2022-05-13 CN claimed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
CN-109701013-B Targeted nano drug delivery system and preparation method thereof 安徽工程大学 2021-07-13 CN claimed
CN-113045774-A Double-network composite hydrogel or hydrogel ball containing nano-silver and preparation method and application thereof 江汉大学 2021-06-29 CN claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
CN-110669110-A Preparation process of RGD cyclized pentapeptide 南京恒远科技开发有限公司 2020-01-10 CN claimed
CN-109701013-A A kind of targeted nanometer drug delivery system and preparation method 安徽工程大学 2019-05-03 CN claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
EP-4714499-A2 POLYAMIDE COMPOUNDS, METHOD FOR PREPARING SAME, AND MEDICAL USE THEREOF Jiangsu NHWA Pharmaceutical Co., Ltd (CN) 2026-03-25 EP disclosed
US-5371076-A ANTIBIOTICS AMERICAN CYANAMID COMPANY (US) 1994-12-06 US disclosed
EP-0618190-A1 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1994-10-05 EP disclosed
WO-1994021673-A1 ALPHA-KETOAMIDE DERIVATIVES AS INHIBITORS OF THROMBOSIS CORVAS INTERNATIONAL, INC. (US) 1994-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP MDM4 3741/4885TP53 1141/4885CASP3 1489/4885
US-20250332299-A1 COMPOUND TARGETING SSTR2, PREPARATION METHOD THEREFOR AND USE THEREOF SSTR2, SSTR5, SSTR3 MDM4 4630/4885TP53 2881/4885CASP3 3801/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 MDM4 884/4885TP53 403/4885CASP3 2158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.