SCHEMBL119459

SCHEMBL119459

O=C(N[C@H](CC1CCCC1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.55
TP53 P04637 3/20 0.55
CASP3 P42574 2/20 0.50
TLR2 O60603 4/20 0.49
MDM2 Q00987 4/20 0.48
KMT2A Q03164 1/20 0.47
SLC17A5 Q9NRA2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29709621 1.00 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL119456 1.00 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL23722984 1.00 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL30062876 0.99 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL119686 0.99 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL29398457 0.99 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL118173 0.99 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL178739 0.99 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL29400667 0.99 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL31437097 0.98 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20090062147-A1 Methods for synthesis of encoded libraries PRAECIS PHARMACEUTICALS INCORPORATED (US) 2009-03-05 US disclosed
US-20090062147-A1 Methods for synthesis of encoded libraries PRAECIS PHARMACEUTICALS INCORPORATED (US) 2009-03-05 US disclosed