SCHEMBL29398457

SCHEMBL29398457

O=C(N[C@@H](CC1CCCCC1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.54
TP53 P04637 3/20 0.54
CASP3 P42574 2/20 0.49
TLR2 O60603 4/20 0.49
MDM2 Q00987 4/20 0.47
KMT2A Q03164 1/20 0.46
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
CTSS P25774 1/20 0.46
CTSK P43235 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119686 1.00 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL29400667 1.00 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL30062876 1.00 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL178739 1.00 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL118173 1.00 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL23722984 0.99 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL119459 0.99 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL119456 0.99 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL29709621 0.99 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL31437097 0.97 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 EP disclosed
US-20260139257-A1 PLIN1 RNAi INTERFERENCE AGENTS ELI LILLY AND CO (US) 2026-05-21 US disclosed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US disclosed
EP-4732286-A2 COMPOSITIONS AND METHODS FOR ENCRYPTING, STORING, AND DECRYPTING INFORMATION IN OLIGOMERS Board of Regents, The University of Texas System (US) 2026-04-29 EP disclosed
US-20260070945-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY 2026-03-12 US disclosed
US-20260049101-A1 TOPICAL TREATMENT OF SKIN CANCER USING OLIGOPEPTIDES BACOBA AG (CH) 2026-02-19 US disclosed
EP-4695268-A1 ANTIBACTERIAL COVALENT PEPTIDE INHIBITORS Université de Bordeaux (FR) 2026-02-18 EP disclosed
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2026-01-22 US disclosed
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS MERCK SHARP & DOHME LLC (US) 2026-01-01 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
WO-2022215745-A1 SUBSTANCE OF NOVEL SIDEROPHORE-TYPE ANTIFUNGAL AGENT (COMPOUND) AND USE OF SAME 国立研究開発法人理化学研究所 2022-10-13 WO disclosed
EP-4069684-A2 COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING ETH Zurich (CH) 2022-10-12 EP disclosed
WO-2022202816-A1 PEPTIDE AND PEPTIDE-CONTAINING COMPOSITION ペプチエイド株式会社 2022-09-29 WO disclosed
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME CORNELL UNIVERSITY 2022-09-15 US disclosed
US-11440938-B2 Stabilized minimal coiled-coil mimetics NEW YORK UNIVERSITY (US) 2022-09-13 US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
EP-4043478-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITING ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-08-17 EP disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 EP disclosed
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-03-22 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11440938-B2 Stabilized minimal coiled-coil mimetics COIL, CALCOCO2, SMC2 MDM4 256/4885TP53 657/4885CASP3 3879/4885
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 MDM4 3040/4885TP53 421/4885CASP3 1560/4885
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries TP53, MDM2, MDM4 MDM4 3/4885TP53 1/4885CASP3 2615/4885
US-20260070945-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1, PDCD1LG2 MDM4 2686/4885TP53 428/4885CASP3 1567/4885
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR MDM4 4874/4885TP53 2182/4885CASP3 1790/4885
US-20260139257-A1 PLIN1 RNAi INTERFERENCE AGENTS PLIN1, PLIN3, PLIN5 MDM4 3255/4885TP53 4176/4885CASP3 2810/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 MDM4 2407/4885TP53 2772/4885CASP3 3274/4885
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH MDM4 2743/4885TP53 3446/4885CASP3 3773/4885
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS KRAS, NRAS, HRAS MDM4 1577/4885TP53 11/4885CASP3 2464/4885
US-20260049101-A1 TOPICAL TREATMENT OF SKIN CANCER USING OLIGOPEPTIDES NGLY1, MC1R, EGFR MDM4 2280/4885TP53 190/4885CASP3 1188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.