SCHEMBL119478

SCHEMBL119478

COc1ccc(C(NC(=O)CC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)c2ccc(OC)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 7/20 0.59
TLR2 O60603 2/20 0.54
MDM4 O15151 3/20 0.50
TP53 P04637 3/20 0.50
CASP3 P42574 1/20 0.46
TNF P01375 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120502 0.91 TLR2 (0.57) MDM2TLR2MDM4TP53CASP3
SCHEMBL119621 0.90 MDM2 (0.56) MDM2TLR2MDM4TP53CASP3
SCHEMBL29561499 0.90 MDM2 (0.56) MDM2TLR2MDM4TP53CASP3
SCHEMBL22444788 0.84 MDM2 (0.63) MDM2TLR2MDM4TP53CASP3
SCHEMBL22444972 0.84 MDM2 (0.63) MDM2TLR2MDM4TP53CASP3
SCHEMBL29540551 0.84 TLR2 (0.61) MDM2TLR2MDM4TP53CASP3
SCHEMBL15083102 0.84 TLR2 (0.61) MDM2TLR2MDM4TP53CASP3
SCHEMBL14445569 0.84 TLR2 (0.61) MDM2TLR2MDM4TP53CASP3
SCHEMBL29540527 0.84 TLR2 (0.61) MDM2TLR2MDM4TP53CASP3
SCHEMBL31647183 0.83 MDM2 (0.56) MDM2TLR2MDM4TP53CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed