SCHEMBL120502

SCHEMBL120502

O=C(CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)NC(c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 2/20 0.57
MDM4 O15151 3/20 0.53
TP53 P04637 3/20 0.53
MDM2 Q00987 6/20 0.50
CASP3 P42574 2/20 0.48
KMT2A Q03164 2/20 0.48
SLC17A5 Q9NRA2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119478 0.91 MDM2 (0.59) TLR2MDM4TP53MDM2CASP3
SCHEMBL119373 0.89 MDM4 (0.55) TLR2MDM4TP53MDM2CASP3
SCHEMBL29540551 0.88 TLR2 (0.61) TLR2MDM4TP53MDM2CASP3
SCHEMBL15083102 0.88 TLR2 (0.61) TLR2MDM4TP53MDM2CASP3
SCHEMBL29540527 0.88 TLR2 (0.61) TLR2MDM4TP53MDM2CASP3
SCHEMBL14445569 0.88 TLR2 (0.61) TLR2MDM4TP53MDM2CASP3
SCHEMBL14997839 0.87 KMT2A (0.58) TLR2MDM4TP53MDM2CASP3
SCHEMBL29400089 0.87 KMT2A (0.58) TLR2MDM4TP53MDM2CASP3
SCHEMBL30338216 0.87 KMT2A (0.58) TLR2MDM4TP53MDM2CASP3
SCHEMBL29908078 0.87 KMT2A (0.58) TLR2MDM4TP53MDM2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed