SCHEMBL119483

SCHEMBL119483

O=C(N[C@H](Cc1cncn1C(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.52
TP53 P04637 3/20 0.52
MDM2 Q00987 7/20 0.46
CASP3 P42574 2/20 0.42
SLC17A5 Q9NRA2 1/20 0.40
TLR2 O60603 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12040111 1.00 MDM4 (0.52) MDM4TP53MDM2CASP3SLC17A5
SCHEMBL12982089 0.89 MDM4 (0.47) MDM4TP53MDM2CASP3
SCHEMBL30340129 0.86 MDM2 (0.53) MDM4TP53MDM2CASP3TLR2
SCHEMBL30340355 0.86 MDM2 (0.53) MDM4TP53MDM2CASP3TLR2
SCHEMBL13470198 0.85 MDM4 (0.52) MDM4TP53MDM2CASP3TLR2
SCHEMBL29615250 0.85 MDM4 (0.54) MDM4TP53MDM2CASP3TLR2
SCHEMBL15729186 0.85 MDM4 (0.54) MDM4TP53MDM2CASP3TLR2
SCHEMBL18795312 0.85 MDM4 (0.54) MDM4TP53MDM2CASP3TLR2
SCHEMBL13470493 0.83 MDM4 (0.50) MDM4TP53MDM2CASP3
SCHEMBL31370482 0.82 MDM4 (0.53) MDM4TP53MDM2CASP3SLC17A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed