Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12982608 | 0.89 | MDM4 (0.42) | MDM4TP53MDM2 | |
| SCHEMBL12040111 | 0.89 | MDM4 (0.52) | MDM4TP53CASP3MDM2 | |
| SCHEMBL119483 | 0.89 | MDM4 (0.52) | MDM4TP53CASP3MDM2 | |
| SCHEMBL30385679 | 0.82 | MDM4 (0.49) | MDM4TP53MDM2 | |
| SCHEMBL30340129 | 0.80 | MDM2 (0.53) | MDM4TP53CASP3MDM2 | |
| SCHEMBL30340355 | 0.80 | MDM2 (0.53) | MDM4TP53CASP3MDM2 | |
| SCHEMBL20106639 | 0.79 | MDM4 (0.47) | MDM4TP53CASP3 | |
| SCHEMBL31494731 | 0.77 | MDM4 (0.47) | MDM4TP53CASP3MDM2 | |
| SCHEMBL13296513 | 0.77 | MDM4 (0.38) | MDM4TP53CASP3MDM2 | |
| SCHEMBL31665894 | 0.77 | PTPN1 (0.49) | MDM4TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732137-B2 | Semi-recombinant preparation of GLP-1 analogues | NOVO NORDISK A/S (DK) | 2017-08-15 | — | — | US | disclosed |
| US-9732137-B2 | Semi-recombinant preparation of GLP-1 analogues | NOVO NORDISK A/S (DK) | 2017-08-15 | — | — | US | disclosed |
| US-20100317057-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2010-12-16 | — | — | US | disclosed |
| US-20100317057-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2010-12-16 | — | — | US | disclosed |