Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CFD | P00746 | 6/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044579 | 0.93 | METTL3 (0.86) | METTL3GAAEGFRMAPTPLA2G4A | |
| SCHEMBL1044577 | 0.93 | METTL3 (0.86) | METTL3GAAEGFRMAPTPLA2G4A | |
| SCHEMBL19829420 | 0.92 | METTL3 (0.88) | METTL3GAAEGFRMAPTCFD | |
| SCHEMBL1104875 | 0.92 | METTL3 (0.88) | METTL3GAAEGFRMAPTCFD | |
| SCHEMBL11948687 | 0.91 | METTL3 (0.69) | METTL3GAAEGFRMAPTCFD | |
| SCHEMBL11948686 | 0.90 | METTL3 (0.76) | METTL3GAAEGFRMAPTCFD | |
| SCHEMBL13596336 | 0.89 | METTL3 (0.77) | METTL3GAAEGFRMAPTCFD | |
| SCHEMBL3245215 | 0.89 | METTL3 (0.71) | METTL3GAAEGFRMAPTPLA2G4A | |
| SCHEMBL11948675 | 0.88 | METTL3 (0.75) | METTL3GAAMAPTCFDPLA2G4A | |
| SCHEMBL13693054 | 0.86 | METTL3 (0.86) | METTL3GAAEGFRMAPTPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232401-B2 | Useful as an anti-HIV agent that particularly shows an anti-HIV action based on an integrase inhibitory activity; for treatment or prophylaxis of AIDS; for example, 6-(2,3-dichlorobenzyl)-1-(2-hydroxyethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | JAPAN TOBACCO INC. (JP) | 2012-07-31 | — | — | US | disclosed |