Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11948829 | 0.91 | ALDH1A1 (0.43) | HTR1AALDH1A1NPSR1MEN1GAA | |
| SCHEMBL11948835 | 0.89 | ALDH1A1 (0.46) | HTR1AALDH1A1NPSR1MEN1GAA | |
| SCHEMBL11948834 | 0.88 | ALDH1A1 (0.38) | HTR1AALDH1A1NPSR1MEN1GAA | |
| SCHEMBL11948838 | 0.85 | POLB (0.39) | HTR1AALDH1A1NPSR1MEN1GAA | |
| SCHEMBL11948839 | 0.83 | ALDH1A1 (0.34) | KDRHTR1AALDH1A1NPSR1MEN1 | |
| SCHEMBL18179596 | 0.82 | KDR (0.44) | KDRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL11948744 | 0.79 | ALDH1A1 (0.39) | HTR1AALDH1A1NPSR1MEN1GAA | |
| SCHEMBL11948818 | 0.79 | KDR (0.49) | KDRALDH1A1NPSR1MEN1GAA | |
| SCHEMBL11948833 | 0.79 | ALDH1A1 (0.39) | HTR1AALDH1A1NPSR1MEN1GAA | |
| SCHEMBL11948760 | 0.78 | ALDH1A1 (0.43) | KDRHTR1AALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167496-B1 | AZO DYES | HUNTSMAN ADV MAT SWITZERLAND (CH) | 2014-09-24 | — | — | EP | disclosed |
| US-8231691-B2 | Azo dyes | HUNTSMAN INTERNATIONAL LLC (US) | 2012-07-31 | — | — | US | disclosed |
| US-8231691-B2 | Azo dyes | HUNTSMAN INTERNATIONAL LLC (US) | 2012-07-31 | — | — | US | disclosed |
| US-20100196676-A1 | AZO DYES | HUNTSMAN INTERNATIONAL LLC (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100196676-A1 | AZO DYES | HUNTSMAN INTERNATIONAL LLC (US) | 2010-08-05 | — | — | US | disclosed |
| WO-2009013122-A2 | AZO DYES | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2009-01-29 | — | — | WO | disclosed |