Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068672 | 0.78 | ERN1 (0.59) | MGAMALOX15KDM4ETSHRACMSD | |
| SCHEMBL208097 | 0.77 | KDM4E (0.64) | MGAMALOX15ALDH1A1KDM4ETSHR | |
| SCHEMBL18918667 | 0.76 | ULK1 (0.59) | ERN1CNR2PIK3CG | |
| SCHEMBL17799551 | 0.76 | MGAM (0.57) | MGAMMAP4K4CSNK1G2CLK4MKNK2 | |
| SCHEMBL31127610 | 0.76 | MGAM (0.57) | MGAMMAP4K4CSNK1G2CLK4MKNK2 | |
| Hydrochloric Acid SCHEMBL29133274 | 0.76 | KDM4E (0.61) | ALOX15ALDH1A1KDM4ETSHRACMSD | |
| SCHEMBL31220211 | 0.75 | CYP1A2 (0.53) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL16512107 | 0.75 | CYP1A2 (0.53) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL3826111 | 0.75 | BIRC5 (0.59) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL18918691 | 0.74 | ULK1 (0.47) | ALOX15KDM4ETSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012098416-A1 | DIARYLACETYLENE HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2012-07-26 | — | — | WO | disclosed |