SCHEMBL1196045

SCHEMBL1196045

CC(C)COC(=O)C1C(c2ccccc2)CCC(c2ccccc2)C1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.51
KDM1A O60341 1/20 0.44
GAA P10253 1/20 0.43
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
FABP7 O15540 4/20 0.43
FABP5 Q01469 3/20 0.43
CACNA1F O60840 1/20 0.41
CACNA1D Q01668 1/20 0.41
CACNA1S Q13698 1/20 0.41
CACNA1C Q13936 1/20 0.41
FABP3 P05413 2/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
NPC1 O15118 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1196044 0.96 PPARG (0.48) PPARGKDM1AALDH1A1TSHRCACNA1F
SCHEMBL4439254 0.80 PPARG (0.53) PPARGGAAALDH1A1TSHRFABP7
SCHEMBL1196562 0.79 MAPT (0.58) ALDH1A1TSHRHTT
SCHEMBL9721811 0.78 MAPK1 (0.51) KDM1AALDH1A1TSHRCACNA1FCACNA1D
SCHEMBL1195508 0.78 EDNRA (0.52) ALDH1A1TSHRFABP7FABP5FABP3
SCHEMBL1196033 0.78 PPARG (0.50) PPARGKDM1AGAAALDH1A1TSHR
SCHEMBL13517176 0.77 HSP90AA1 (0.39) PPARGALDH1A1TSHRCACNA1FCACNA1D
SCHEMBL1196186 0.77 PPARG (0.51) PPARGALDH1A1CHRM2CHRM4CHRM5
SCHEMBL1196190 0.76 SLC6A3 (0.48)
SCHEMBL1196367 0.74 PPARG (0.59) PPARGALDH1A1TSHRCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1845113-B1 SOLID TITANIUM CATALYST COMPONENT, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2015-04-01 EP disclosed
US-7888438-B2 A solid titanium catalyst component comprising titanium, magnesium, halogen, and a C5-C10 carbocyclic diester, and an organometallic component; moldable polyolefins having broad molecular weight distribution MITSUI CHEMICALS, INC. (JP) 2011-02-15 US disclosed
US-7649062-B2 Solid titanium catalyst component, catalyst for polymerization of olefin and process for producing olefin polymer MITSUI CHEMICALS, INC. (JP) 2010-01-19 US disclosed
US-20090069515-A1 Solid Titanium Catalyst Component, Catalyst for Polymerization of Olefin and Process for Producing Olefin Polymer MITSUI CHEMICALS,INC. (JP) 2009-03-12 US disclosed
US-20080125555-A1 Catalyst for olefin polymerization and process for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2008-05-29 US disclosed
US-20080097050-A1 Solid titanium catalyst component, catalyst for polymerization of olefin and process for producing olefin polymer MITSUI CHEMICALS, INC. (JP) 2008-04-24 US disclosed
EP-1845113-A1 SOLID TITANIUM CATALYST COMPONENT, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER Mitsui Chemicals, Inc. (JP) 2007-10-17 EP disclosed