Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | REN | P00797 | 8/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124149 | 0.95 | ALDH1A1 (0.57) | ALDH1A1SIGMAR1REN | |
| SCHEMBL16118740 | 0.90 | ALDH1A1 (0.48) | ALDH1A1PPARGPTGESALOX5SIGMAR1 | |
| SCHEMBL11960850 | 0.86 | PPARG (0.58) | PPARGPTGESALOX5SIGMAR1ALOX15 | |
| SCHEMBL15111742 | 0.85 | ATM (0.53) | ALDH1A1PPARGS1PR2S1PR1S1PR3 | |
| SCHEMBL15111743 | 0.85 | ATM (0.53) | ALDH1A1PPARGS1PR2S1PR1S1PR3 | |
| SCHEMBL18313824 | 0.85 | PPARG (0.41) | ALDH1A1PPARGPTGESALOX5SIGMAR1 | |
| SCHEMBL19509032 | 0.84 | PPARG (0.56) | ALDH1A1PPARGPTGESALOX5SIGMAR1 | |
| SCHEMBL10084808 | 0.83 | ACACB (0.55) | PPARG | |
| SCHEMBL13126082 | 0.83 | ACACB (0.55) | PPARG | |
| SCHEMBL12473156 | 0.83 | ACACB (0.55) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252578-B1 | CONJUGATES FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS | UNIV RAMOT (IL) | 2012-08-01 | — | — | EP | disclosed |