Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11961415 | 0.83 | NR3C1 (0.48) | NR3C1PGRESR1ARL3MBTL1 | |
| SCHEMBL11961986 | 0.78 | NR3C1 (0.51) | NR3C1PGRESR1AR | |
| SCHEMBL11960998 | 0.76 | NR3C1 (0.34) | NR3C1PGRESR1AR | |
| SCHEMBL13604148 | 0.74 | NR3C1 (0.49) | NR3C1PGRESR1AR | |
| SCHEMBL14196989 | 0.74 | NR3C1 (0.55) | NR3C1PGRESR1AR | |
| SCHEMBL13604157 | 0.73 | NR3C1 (0.48) | NR3C1PGRESR1AR | |
| SCHEMBL12864097 | 0.73 | NR3C1 (0.52) | NR3C1PGRESR1ARL3MBTL1 | |
| SCHEMBL11961969 | 0.70 | NR3C1 (0.55) | NR3C1PGRESR1AR | |
| SCHEMBL12864651 | 0.70 | NR3C1 (0.53) | NR3C1PGRESR1AR | |
| SCHEMBL13674605 | 0.70 | NR3C1 (0.39) | NR3C1PGRARL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708701-B1 | MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-KB ACTIVITY AND USE THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2012-08-01 | — | — | EP | disclosed |