⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11961580 | 0.81 | — | — | |
| SCHEMBL13448109 | 0.76 | — | — | |
| SCHEMBL24092138 | 0.69 | — | — | |
| SCHEMBL24092141 | 0.65 | — | — | |
| SCHEMBL16411668 | 0.58 | — | — | |
| SCHEMBL23452140 | 0.56 | LMNA (0.31) | — | |
| SCHEMBL20463145 | 0.56 | — | — | |
| SCHEMBL16385694 | 0.55 | — | — | |
| SCHEMBL26027159 | 0.54 | — | — | |
| SCHEMBL15853311 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8497285-B2 | Therapy of autoimmune colitis using a TIP60 inhibitor | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-07-30 | — | — | US | disclosed |
| US-20120202848-A1 | THERAPY OF AUTOIMMUNE COLITIS USING A TIP60 INHIBITOR | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-08-09 | — | — | US | disclosed |