Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deferitazole SCHEMBL1270380 | 1.00 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| Deferitazole SCHEMBL1270379 | 1.00 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| Deferitazole SCHEMBL17209568 | 1.00 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| Deferitazole SCHEMBL29379651 | 1.00 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11963290 | 1.00 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1317324 | 1.00 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11963399 | 1.00 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1314942 | 1.00 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1314947 | 1.00 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| Deferitazole SCHEMBL15012242 | 0.99 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846731-B2 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-8846731-B2 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-8829197-B2 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-8829197-B2 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-20120270911-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270911-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120202857-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202857-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-8063227-B2 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-8063227-B2 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110160257-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110160257-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-20100137383-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100137383-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| WO-2010009120-A2 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160257-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, SLC39A11 | KMT2A 3963/4885MEN1 1802/4885SMN1; SMN2 1962/4885 |
| US-20120202857-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, SLC39A11 | KMT2A 3881/4885MEN1 1725/4885SMN1; SMN2 1906/4885 |
| US-20120270911-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, SLC39A11 | KMT2A 3881/4885MEN1 1725/4885SMN1; SMN2 1906/4885 |
| US-20100137383-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, SLC39A11 | KMT2A 3963/4885MEN1 1802/4885SMN1; SMN2 1962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.