Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11966991 | 1.00 | THRB (0.44) | THRBGAATHRAMEN1KMT2A | |
| SCHEMBL11966993 | 0.99 | THRB (0.45) | THRBGAATHRAMEN1KMT2A | |
| SCHEMBL11966997 | 0.95 | THRB (0.43) | THRBGAATHRAMEN1KMT2A | |
| SCHEMBL11966992 | 0.90 | THRB (0.41) | THRBGAAKMT2AL3MBTL1HPGD | |
| SCHEMBL28748172 | 0.89 | TP53 (0.48) | THRBKMT2AL3MBTL1TSHRTP53 | |
| SCHEMBL18806545 | 0.88 | THRB (0.48) | THRBTHRAMEN1KMT2AHPGD | |
| SCHEMBL11966994 | 0.88 | GAA (0.41) | THRBGAATHRAKMT2AL3MBTL1 | |
| SCHEMBL32678537 | 0.86 | THRB (0.46) | THRBTHRATSHR | |
| SCHEMBL32678535 | 0.86 | THRB (0.46) | THRBTHRATSHR | |
| SCHEMBL32678536 | 0.86 | THRB (0.46) | THRBTHRATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241749-B2 | Barrier laminate, gas barrier film, and device using the same | FUJIFILM CORPORATION (JP) | 2012-08-14 | — | — | US | disclosed |