Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.75 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.75 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.75 |
| ▸ | MARK3 | P27448 | 2/20 | 0.75 |
| ▸ | PLK1 | P53350 | 2/20 | 0.75 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.75 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.62 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.62 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.62 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.62 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.62 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 15/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345697 | 0.99 | MAP4K4 (0.76) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1966766 | 0.99 | MAP4K4 (0.76) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL12391817 | 0.99 | MAP4K4 (0.76) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL11969015 | 0.98 | MAP4K4 (0.75) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| Potassium SCHEMBL11969024 | 0.98 | MAP4K4 (0.75) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| Methyl Alcohol SCHEMBL11969263 | 0.98 | MAP4K4 (0.75) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL11969002 | 0.98 | MAP4K4 (0.75) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| Isopropyl Alcohol SCHEMBL11969780 | 0.97 | MAP4K4 (0.73) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL2342646 | 0.97 | MAP4K4 (0.77) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| Alcohol SCHEMBL11969022 | 0.96 | MAP4K4 (0.71) | MAP4K4MINK1DYRK3MARK3PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214848-A1 | [1,2,4]OXADIAZOL-3-YL ACID SALTS AND CRYSTALLINE FORMS AND THEIR PREPARATION | ABBOTT LABORATORIES (US) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214848-A1 | [1,2,4]OXADIAZOL-3-YL ACID SALTS AND CRYSTALLINE FORMS AND THEIR PREPARATION | UACA, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TUBA3C | MAP4K4 1622/4885MINK1 1815/4885DYRK3 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.