Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 7/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313177 | 0.79 | ARG1 (0.39) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL8332356 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL10224 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL127805 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL8332360 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL222059 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL8332353 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL10225 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL21114356 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL5018669 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424573-B1 | LABELED MOLECULAR IMAGING AGENTS, METHODS OF MAKING AND METHODS OF USE | GEN ELECTRIC (US) | 2019-01-16 | — | — | EP | disclosed |
| US-8834839-B2 | Labeled molecular imaging agents, methods of making and methods of use | GENERAL ELECTRIC COMPANY (US) | 2014-09-16 | — | — | US | disclosed |
| EP-2424573-A2 | LABELED MOLECULAR IMAGING AGENTS, METHODS OF MAKING AND METHODS OF USE | General Electric Company (US) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010125068-A2 | LABELED MOLECULAR IMAGING AGENTS, METHODS OF MAKING AND METHODS OF USE | GENERAL ELECTRIC COMPANY (US) | 2010-11-04 | — | — | WO | disclosed |
| US-20100272641-A1 | LABELED MOLECULAR IMAGING AGENTS, METHODS OF MAKING AND METHODS OF USE | GENERAL ELECTRIC COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100272641-A1 | LABELED MOLECULAR IMAGING AGENTS, METHODS OF MAKING AND METHODS OF USE | SLC7A11, SLC3A2, SLC1A2 | ARG1 1580/4885ARG2 439/4885NOS2 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.