SCHEMBL11972053

SCHEMBL11972053

CCOP(=O)(O)ON(C)C

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
PPARD Q03181 2/20 0.41
ACHE P22303 1/20 0.39
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MVD P53602 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29222825 0.82 LPAR3 (0.38) MVDMEN1KMT2A
SCHEMBL9328046 0.79 TSHR (0.40) TSHRPPARDACHETP53TDP1
Diethyl Hydrogen Phosphate SCHEMBL93056 0.79
Diethyl Hydrogen Phosphate SCHEMBL27294237 0.79 TSHR (0.56) TSHRPPARDTP53TDP1
SCHEMBL7103813 0.79 CA2 (0.35) TDP1
Diethyl Hydrogen Phosphate SCHEMBL11752938 0.76 TSHR (0.53) TSHRPPARDTP53TDP1
Diethyl Hydrogen Phosphate SCHEMBL17008846 0.76 TSHR (0.53) TSHRPPARDTP53TDP1
Diethyl Hydrogen Phosphate SCHEMBL3133022 0.76 TSHR (0.53) TSHRPPARDTP53TDP1
Diethyl Hydrogen Phosphate SCHEMBL8431810 0.76 TSHR (0.53) TSHRPPARDTP53TDP1
Diethyl Hydrogen Phosphate SCHEMBL4948463 0.76 TSHR (0.53) TSHRPPARDTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105814092-B Composition for hydrophilic cured product 三井化学株式会社 2018-09-21 CN disclosed
CN-107430213-A Hydrophilic optical feature monofilm and its layered product 三井化学株式会社 2017-12-01 CN disclosed
CN-103827073-B Method for recovering valuable products in the course of producing dialkylaminoalkyl (meth) acrylates ARKEMA FRANCE (FR) 2016-03-02 CN disclosed
EP-2825642-A1 ISOLATED PON1 POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME AND USES THEREOF IN TREATING OR PREVENTING ORGANOPHOSPHATE EXPOSURE ASSOCIATED DAMAGE Yeda Research and Development Co. Ltd. (IL) 2015-01-21 EP disclosed
CN-103827073-A Method for recovering valuable products in the course of producing dialkylaminoalkyl acrylates ARKEMA FRANCE 2014-05-28 CN disclosed
US-8735124-B2 Isolated PON1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2014-05-27 US disclosed
WO-2013136335-A1 ISOLATED PON1 POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME AND USES THEREOF IN TREATING OR PREVENTING ORGANOPHOSPHATE EXPOSURE ASSOCIATED DAMAGE YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-09-19 WO disclosed
US-20120213834-A1 ISOLATED PON1 POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME AND USES THEREOF IN TREATING OR PREVENTING ORGANOPHOSPHATE EXPOSURE ASSOCIATED DAMAGE YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2012-08-23 US disclosed
CN-1017618-B PROCESS FOR PREPARATION OF PENTAFLUOROPHENY2, 2-DIMETHY 1-3-FORMYL CYCLOPROPANE CARBOXYLATE ROUSSEL UCLAF (FR) 1992-07-29 CN disclosed
CN-87107450-A Preparation 2, the method for 2-dimethyl-3-formyl radical-cyclopropane-carboxylic acid pentafluorophenyl group methyl esters 1988-06-22 CN disclosed