Quinazoline

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Quinazoline SCHEMBL760383	0.84	EGFR (0.62)	EGFRPIK3CDPIK3CATDO2KDM4E
	Quinazoline SCHEMBL760382	0.82	EGFR (0.65)	EGFRPIK3CDPIK3CATDO2KDM4E
	Naphthalene SCHEMBL29363450	0.82	KDM4E (0.46)	TDO2QPCTQPCTLKDM4EALDH1A1
	Naphthalene SCHEMBL15819597	0.82	KDM4E (0.46)	TDO2QPCTQPCTLKDM4EALDH1A1
	Naphthalene SCHEMBL9738608	0.82	KDM4E (0.46)	TDO2QPCTQPCTLKDM4EALDH1A1
	Quinazoline SCHEMBL5920	0.82	EGFR (1.00)	EGFRPIK3CDPIK3CATDO2KDM4E
	Quinazoline SCHEMBL29490398	0.82	EGFR (1.00)	EGFRPIK3CDPIK3CATDO2KDM4E
	Quinazoline SCHEMBL22833783	0.82	EGFR (1.00)	EGFRPIK3CDPIK3CATDO2KDM4E
	Benzimidazole SCHEMBL28307511	0.82	KDM4E (0.48)	TDO2QPCTQPCTLKDM4EALDH1A1
	Quinazoline SCHEMBL29356169	0.82	EGFR (1.00)	EGFRPIK3CDPIK3CATDO2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.