Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130827 | 0.89 | POLB (0.48) | PTGS1PTGS2ALOX5EPHX2CHRM2 | |
| SCHEMBL18016713 | 0.89 | POLB (0.48) | PTGS1PTGS2ALOX5EPHX2CHRM2 | |
| SCHEMBL11907189 | 0.89 | PTGS1 (0.59) | PTGS1PTGS2ALOX5EPHX2CHRM2 | |
| SCHEMBL10343356 | 0.87 | POLB (0.50) | PTGS1PTGS2ALOX5EPHX2CHRM2 | |
| SCHEMBL8143743 | 0.81 | POLB (0.52) | ALOX5EPHX2CHRM2CHRM5CHRM1 | |
| SCHEMBL8921829 | 0.80 | EPHX2 (0.57) | PTGS1PTGS2ALOX5EPHX2CHRM2 | |
| SCHEMBL10878735 | 0.80 | EPHX2 (0.57) | PTGS1PTGS2ALOX5EPHX2CHRM2 | |
| SCHEMBL30889345 | 0.80 | EPHX2 (0.57) | PTGS1PTGS2ALOX5EPHX2CHRM2 | |
| SCHEMBL3924849 | 0.80 | EPHX2 (0.57) | PTGS1PTGS2ALOX5EPHX2CHRM2 | |
| SCHEMBL16753020 | 0.80 | EPHX2 (0.57) | PTGS1PTGS2ALOX5EPHX2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921582-B2 | Oligo- and polyfurans, preparation and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2014-12-30 | — | — | US | disclosed |
| US-20140179934-A1 | OLIGO- AND POLYFURANS, PREPARATION AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2014-06-26 | — | — | US | disclosed |
| US-8759550-B2 | Oligo- and polyfurans, preparation and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2014-06-24 | — | — | US | disclosed |
| US-20120209013-A1 | OLIGO- AND POLYFURANS, PREPARATION AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO.LTD (IL) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179934-A1 | OLIGO- AND POLYFURANS, PREPARATION AND USES THEREOF | PUF60, POLI, DHFR | PTGS1 2129/4885PTGS2 2419/4885ALOX5 432/4885 |
| US-20120209013-A1 | OLIGO- AND POLYFURANS, PREPARATION AND USES THEREOF | PUF60, POLI, DHFR | PTGS1 2129/4885PTGS2 2419/4885ALOX5 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.