Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3513303 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1LMNAKMT2APOLB | |
| SCHEMBL10152684 | 0.78 | MAPT (0.46) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL22471423 | 0.76 | MAPT (0.59) | MAPTALDH1A1LMNAKMT2APOLB | |
| SCHEMBL4383340 | 0.74 | MAPT (0.52) | MAPTALDH1A1LMNAKMT2APOLB | |
| SCHEMBL28196822 | 0.74 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAKMT2APOLB | |
| SCHEMBL18876391 | 0.73 | MAPT (0.51) | MAPTALDH1A1LMNAKMT2APOLB | |
| SCHEMBL14851247 | 0.72 | MAPT (0.54) | MAPTALDH1A1LMNAKMT2APOLB | |
| SCHEMBL17422247 | 0.71 | MAPT (0.55) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL28980384 | 0.71 | ALDH1A1 (0.44) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL2448576 | 0.71 | MAPT (0.64) | MAPTALDH1A1LMNATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208997-A1 | NOVEL COMPOUND HAVING HETEROCYCLIC RING | SUZUKI HIDEYUKI (JP) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208997-A1 | NOVEL COMPOUND HAVING HETEROCYCLIC RING | OXA1L, MRPL21, TOP1 | MAPT 4600/4885ALDH1A1 317/4885LMNA 3275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.