⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155527 | 1.00 | — | — | |
| SCHEMBL9798205 | 0.91 | — | — | |
| SCHEMBL9797595 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL9798200 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL9797972 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL9797560 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL9797711 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL9798259 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL9797478 | 0.88 | CES2 (0.48) | — | |
| SCHEMBL9797510 | 0.88 | CES2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130115168-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2013-05-09 | — | — | US | disclosed |
| US-8257680-B1 | Catalytic radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120207677-A1 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION | 2012-08-16 | — | — | US | disclosed |
| US-20100215578-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2010-08-26 | — | — | US | disclosed |
| US-7632485-B2 | Catalytic radiofluorination | MASSACHUSETTS GENERAL HOSPITAL (US) | 2009-12-15 | — | — | US | disclosed |